yes you can flash a used one thru gm site  even tis2000. then go to bcm/special function/module setup. it is also a good idea to program vtd even if the vehicle starts to avoid future issues with theft security. tpms needs to be reprogram as well. 2 ways to do it either go to bcm/remote control module/tpms and set it up or simply turn key on press lock and unlock assuming the fob works until the horn sounds, start taking air out the  left front tire slowly until you hear the horn sound again then work your way clockwise around the vehicle until all for horn sounds are complete. this bcm will fit many gm trucks from 03 to 07 all having different options so for sure it has to be flash for the specific truck or .some features may not work correctly or at all. good luck

Glad to help. On the tpms this sensors sometimes go into a deep sleep, retry the
procedure it may wake up. Spend a little more time on that wheel taking air out slowly
until you hear the horn sound then continue with the rest. Regardinng crank relearn
make sure the brake s/w works and follow all requirements or it will fail. Good luck
buddy.

no problem glad to help. if your interested in tis2000 software let me know by email. good price and I can configure it to just any passthru device. its best with an mdi though original or clone don't matter.